Immunological Surveillance

An Immunological Approach to Raising Alarms in Video Surveillance

Inspired by the human immune system, and in particular the negative selection algorithm, we propose a learning mechanism that enables the detection of abnormal activities. Three detectors for detecting abnormal activity are generated using negative selection. Tracks gathered by people’s movements in a room are used for experimentation and results have shown that the classifier is able to discri...

Editorial: Molecules Balancing Immunological Surveillance against Cancer and Autoimmune Diseases

The innate and the adaptive immune systems work in concert to deal with pathologies introduced by internal and external factors (e.g., viruses, bacteria, and fungi) – some of which may be associated with the development of autoimmune and cancerous cells. Mechanistically, there are internal factors that are responsible for the hypo-and hyperfunction of immune tolerance apparatus. Consequently, i...

Immune surveillance against a solid tumor fails because of immunological ignorance.

Many peripheral solid tumors such as sarcomas and carcinomas express tumor-specific antigens that can serve as targets for immune effector T cells. Nevertheless, overall immune surveillance against such tumors seems relatively inefficient. We studied immune surveillance against a s.c. sarcoma expressing a characterized viral tumor antigen. Surprisingly, the tumor cells were capable of inducing ...

Immunological Basis of Neurological Diseases

Clinical neurology has been traditionally considered as an academic speciality in which the specialist regurgitates his/her knowledge of neurology without being able to do much for the patient. This attitude is no longer acceptable. Surge of information and discoveries in neurosciences within the last two decades translated into therapeutic interventions which is literally life saving in some o...

Seaweeds: Some Pharmaco-Immunological Effects